Deletion of the adenosine A 2A receptor increases the survival rate in a mice model of polymicrobial sepsis

Deletion of the adenosine A 2A receptor increases the survival rate in a mice model of polymicrobial sepsis

We aim to investigate the role of A2A receptor in peritonitis-related sepsis by injection of a fecal solution (FS) as a model of polymicrobial infection. C57/black J6 wild-type (WT) and A2A-deficient mice (A2AKO) were exposed to sepsis induced by intraperitoneal injection of a FS (FS-induced periton...

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Weitere Verfasser: Meriño, Miguel (coautor), San Martín, Sebastián (coautor), Sandaña, Pedro (coautor), Herlitz, Kurt (coautor), Aguayo, Claudio (coautor), Godoy, Alejandro (coautor), Torres-Vergara, Pablo Torres-Vergara (coautor), Gonzalez, Marcelo (coautor), Troncoso, Felipe (coautor), Acurio, Jesenia (coautor), Escudero, Carlos (coautor)
Format: E-Book
Sprache:Englisch
Schlagworte:
Sepsis
A2A receptor
Adenosine
Immune response
Endothelial damage
Online-Zugang:https://repositoriobiblio.unach.cl/handle/123456789/1493
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