SiNPle, Fast and Sensitive Variant Calling for Deep Sequencing Data

SiNPle, Fast and Sensitive Variant Calling for Deep Sequencing Data

Este documento propone un software rp̀ido y efectivo para la deteccin̤ de variantes llamado SiNPle (Simplified Inference of Novel Polymorphisms from Large coveragE). El software se basa en el enfoque Bayesiano para computar la probabilidad de que una variante no sea generada por errores de secuencia...

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Bibliografske podrobnosti
Drugi avtorji: Ferretti Luca, Tennakoon Chandana, Silesian Adrian, Freimanis Graham, Ribeca Paolo, MDPI
Format: Knjiga
Jezik:angleščina
Teme:
Biologa̕ molecular
Ingeniera̕ de software
Molecular biology
Software engineering
Secuenciacin̤ de nueva generacin̤
Variantes de baja frecuencia
Poblaciones heterl̤ogas
Modelo Bayesiano
Next generation sequencing
Low-frequency variants
Heterogeneous populations
Bayesian modelling
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SiNPle, Fast and Sensitive Variant Calling for Deep Sequencing Data

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